these are, and always will be, my FAVORITE animations for learning and exploring molecular biology. you are a legend, Drew Berry! thank you for these masterpieces
One of the biggest ‘aha!’ moments in my life came form watching one of your first videos. It gave me a glimpse of understanding what we are made off and how life works in general on a molecular level. Thank your for allowing this. And as I greatly appreciate your efforts to ‘rhythm’ the movement I would also love to see the real randomness in one or your videos. Thank your for your amazing work.
Drew's animations are just staggering and reflects on his extraordinary ability to collate literally decades worth of molecular research. Indeed built on the shoulders of Nobel giants. Drew often references Brownian motion to basically move the "soup" around to instigate enzymatic reactions within the cell and this has puzzled me whether it's sufficient. Which led me to latest research from Harvard that the cummulative movement of all of the molecular motors such as dynein and kinesin produce waves in the soup so that it aids reactions. Totally fascinating from my humble I.T. background that I can view in my life time the intricate level of life itself. Please do not stop showing us such molecular marvels. I'd personally vote Drew for a knighthood for his contribution to understanding biological functions.
I asked for a behind-the-scenes video, and you guys delivered! Seriously, this was exactly the kind of thing I had hoped you'd make. You are all awesome!
As a retired computer tech, hardware/software installation/support, I'm glad you told us a bit about your path through your career. It seems you started out around the same time as I did, and like you, I remember how computer graphics evolved, CGA, EGA, SVGA, all those things that were new to us, and growing by the minute.
Honestly, the first time I ever saw an animation similar to this (it was likely based off your work or might actually have _been_ yours) that showcased how the mitochondria powers the cell with these tiny little rotors spinning, it absolutely blew my mind. I couldn't help but make the comparison with how _we_ make power for our human-scale use. The molecular machinery literally looks and seemingly acts just like the steam turbines of power stations, or water turbines of hydro-electric dams. And here we humans thought _we_ invented this method first ... turns out nature _just_ beat us by, oh about 1.45 _billion_ years or so LOL
When a work sideline turns into new branch of molecular biology. The AI engine will create a new research tool from an illustration system. Well done Drew. Cheers Pierre
I'm not a biologist, I'm a mechanical engineer, but it's been some years that I'm into biology and i see videos and seminars just because it's so amazing to think that there are trillions of this tiny machines inside me and every living creature and works perfectly every time, and it's more amazing to think about how this mechanism apeard on earth and evolved, it seems a very patient engineer just configred all these stuffs and tested them and optimized them. A few years ago after i learned all of these, i said to my self if someone solve the protein fold problem, a boom of research and development would initiate, and here we are with alphafold, every day i see some paper that they discovered something new with this technology
Wanting the backbone of the apoptosome on the side of my back or as a full sleeve for a tattoo! Happy you're inspired-what'd you major? Congrats, Lee! 🎉
one neat thing about alpha fold is it gives a confidence score along with the domains it predicts. i've messed around with it some, and it definitely doesn't get everything right.
This is pure scientific gold! Thank you so much. I am a science dad too and I used your videos with my kids. They just love this! It makes them and me ask so many interesting questions❤. A game for VR wpuld be more than awesome! I imagine to look at labeled or highlighted levels of abstraction or focus like in your videos, all in a loop to explore all the reactions. A time zoom to watch true brownian motion would be the cherry on top.
New to your work guys and am blown away by the depth of understanding to present such sophisticated visual aids. Really happy and less despair in this information age that you guys rally the diligent and dedicated to show the evidence in terms comprehensible by many. Australians as a very good axample rather than cringeworthy underdone blowhards. You save lives, 54 years old and lost for life stoked by you guys. Not dead yet .. all eyes and ears. Cheers, Damo
Thanx. It’s been a deep dive on RUclips couple of off days. I watched the history of civilization, all the wars and destruction. Then I watched a couple of physics videos, I know if I keep at it I’ll get it! 🤣🤣🤣 And then I found you guys!
Incredible work sir. But I am astounded. How can all this near infinite complexity work altogether at once, mind boggling so, multiple machines in perfect harmony and people still think it just happened. I don't have that kind of faith. I would have a better chance of jumping off the earth, getting to Jupiter and back, holding my breath the whole time and landing whole back at my starting point on earth than the common assumptions of materialism. To say it has the "appearance" of design is a death defying leap of presumption. It must take incredible, awesome faith that defies logic to think it's all by chance.
As AI plays a greater role in clarifying movements and interactions of these molecular processes, it becomes more important to UPDATE previous depictions so that research can be further advanced. I hope there is one website with all of these previous videos (dated) that will soon indicate AI enhancements to them.
1:55 omg, i used to play that game as a kid. I literally had to hack the game files(on PC) - copying the files from a previous level to haphazardly replace the CORRUPT final level files - to even be able to play the final level of this game (otherwise it would never complete loading!). I only learned to do that after a number of years too, some of my first experience fixing PC software problems, stay at it kids & come back to old problems! 😉
Incredibly valuable work which has greatly enriched the learning and understanding of my high school students, I look forward to seeing this in VR; and why not have a video game too!!?
Your animations have amazed and astounded me for many years. Thank you deeply, Drew. Many of the inner workings of our bodies are no longer unimaginable, and in fact, are extremely beautiful.
Brilliant. PDH complex is the most astonishing enzyme. I would suggest to design animation for hemoglobin binding and releasing molecular oxygen with the conformational changes of oxy- and deoxy- Hb. Needles to say with the role of heme prosthetic group. Thank you.
Haemoglobin and Sickle Cell Anaemia animation, originally created 20 years ago. Not as advanced as our recent productions ruclips.net/video/-1_qkwQkB_c/видео.htmlsi=jSMaR0pxmKk-GKCi
太酷了,這樣視覺化學習很容易理解神奇複雜細胞運作?" 美極了,由衷感謝! So cool! Visualization is more easier to help us to learn the amazing complexity of cell operation. Great! Thank you all.
This video touches on so many professions, technologies & disciplines. I am an Industrial Designer; the science, information & technology shared in this video is supremely applicable to my industry. Please keep on your mission of information sharing & science education.
Remember memorizing the Krebs/ Citric Acid cycle out of photocopied pages in a binder your Professor made you buy at the college bookstore for $100? Now the kids these days have this! I'm happy for the new generation though, they have more information presented in an understandable,visual learning format!
Thank you for your time and veracity in this journey you've taken, Berry! Great to see more recent uploads while soon to complete an AS in chemistry while transferring to university for biochem. Thanks again!! ⭐
Great work! Thank you for the insight in your workflow. The integration of game engines is a (...wait for it...) game changer ;-) and I'd love to hear more about this!
Anyone know more animators/channels that make videos like this? I want more molecular biology animations that depict Brownian Motion, with molecules modeled by atoms instead of electron surface. It's nice to see the inside of a mitochondrion; I am more interested to see the inner workings of free living or parasitic prokaryotes.
Understands the nature of what he depicts miraculously. He is a true Michelangelo of our time. If I could make a wish, I would like to see a short movie of a fish being eaten, digested, build in and respirated.
You are an amazing human, thank you for simplifying such a complex biological mechanical structures and mechanism to easily understandable chunks. Thank you for your work. Love your channel and your passion.
Nooooo, the réal Drew Berry??? :o You're my legend... Science has always been my big passion, and because of you I'm really fascinated by animation.. But I haven't found any project yet to practice both together...
Thank you so much You guys have helped me excell in my knowledge of the Cells I think Dyslexic people will get the Cells We think in puzzles I never thought in a million years I would get Cellular Biology....thanks guys Belfast Ireland 🇮🇪
You called yourself a "dinosaur" because you learned techniques in the 90's... I attended a talk given by James Blin, a pioneer in animation who worked on the famous "Mechanical Universe" series. He wrote them in FORTRAN.
I was wondering how these incredible animations were made - thank you so much for sharing! It would be amazing to see this running in VR. Unity has good VR support, so it would mostly depend on what kind of performance you get since VR generally requires more than 2x the compute for rendering than does a 'flat' game.
I agree! Wish it had Drew show us a version of the more chaotic looking realistic movements, timing, and density of the individual components. He and his team do a phenomenal job of interpreting and rendering the complexities of what makes life possible. Absolutely fascinating and wondrous! ❤
Those molecular dynamics simulations are very nice. However, besides the length scales shown on the simulations, it will be very nice if they could also have the time scale shown as well.
This is considered science? Yes of course. Is this art? INDEED. Is this architecture? Obviously. Engineering? Certainly. Computer science? Of course. But that's how our Lord works. These are his instruments.
How those molecules which form the ATP molecule know where to go to become ATP? It was mentioned in the animation "enzymes bring together reactants", but nothing more. How smooth is this process in reality? Like each cycle of the rotor creates exactly 3 molecules each time?
Wow... While i still don´t understand why you call Maya a game engine, i understand that the animations skillset of maya is on blockbusterlevel.. But do you also use tools like Unreal for the "REaltime" Part? it´s realy mesmerising.. If i was young again, this could be something for me to study too.. But now as my son studies something like this, i know how much you have to learn to get there
Many thanks for the insightful info! Your videos keep inspiring me to try something similar and I wondered how would simulating the Brownian motion work. Never thought of using a game engine, great idea!
these are, and always will be, my FAVORITE animations for learning and exploring molecular biology.
you are a legend, Drew Berry! thank you for these masterpieces
Yes, thank you Berry
i would pay my entire life savings for this to be a video game. imagine exploring this in VR?!!
Walking around the electron transport chain lol I’d flip out it’d be so cool
@@FerociousPancake888 DOOCTORS CALM DOWN
When I saw the stochastic movement in the videos, I knew it was something different. It's incredibly excellent work.
One of the biggest ‘aha!’ moments in my life came form watching one of your first videos. It gave me a glimpse of understanding what we are made off and how life works in general on a molecular level. Thank your for allowing this.
And as I greatly appreciate your efforts to ‘rhythm’ the movement I would also love to see the real randomness in one or your videos.
Thank your for your amazing work.
Drew's animations are just staggering and reflects on his extraordinary ability to collate literally decades worth of molecular research. Indeed built on the shoulders of Nobel giants. Drew often references Brownian motion to basically move the "soup" around to instigate enzymatic reactions within the cell and this has puzzled me whether it's sufficient. Which led me to latest research from Harvard that the cummulative movement of all of the molecular motors such as dynein and kinesin produce waves in the soup so that it aids reactions. Totally fascinating from my humble I.T. background that I can view in my life time the intricate level of life itself. Please do not stop showing us such molecular marvels. I'd personally vote Drew for a knighthood for his contribution to understanding biological functions.
I asked for a behind-the-scenes video, and you guys delivered! Seriously, this was exactly the kind of thing I had hoped you'd make. You are all awesome!
As a retired computer tech, hardware/software installation/support, I'm glad you told us a bit about your path through your career. It seems you started out around the same time as I did, and like you, I remember how computer graphics evolved, CGA, EGA, SVGA, all those things that were new to us, and growing by the minute.
Honestly, the first time I ever saw an animation similar to this (it was likely based off your work or might actually have _been_ yours) that showcased how the mitochondria powers the cell with these tiny little rotors spinning, it absolutely blew my mind. I couldn't help but make the comparison with how _we_ make power for our human-scale use. The molecular machinery literally looks and seemingly acts just like the steam turbines of power stations, or water turbines of hydro-electric dams. And here we humans thought _we_ invented this method first ... turns out nature _just_ beat us by, oh about 1.45 _billion_ years or so LOL
When a work sideline turns into new branch of molecular biology. The AI engine will create a new research tool from an illustration system. Well done Drew. Cheers Pierre
I'm not a biologist, I'm a mechanical engineer, but it's been some years that I'm into biology and i see videos and seminars just because it's so amazing to think that there are trillions of this tiny machines inside me and every living creature and works perfectly every time, and it's more amazing to think about how this mechanism apeard on earth and evolved, it seems a very patient engineer just configred all these stuffs and tested them and optimized them.
A few years ago after i learned all of these, i said to my self if someone solve the protein fold problem, a boom of research and development would initiate, and here we are with alphafold, every day i see some paper that they discovered something new with this technology
Can't get enough of this kind of animation. My favourite is the movement of pseudopodia.
This is fantastic Drew! Your 2006 animation of apoptosis inspired me to complete my PhD. Would
love to see you do this as a Wednesday seminar.
Wanting the backbone of the apoptosome on the side of my back or as a full sleeve for a tattoo! Happy you're inspired-what'd you major? Congrats, Lee! 🎉
one neat thing about alpha fold is it gives a confidence score along with the domains it predicts. i've messed around with it some, and it definitely doesn't get everything right.
I. LOVE. THESE. VIDEOS..! they're Art and Science and learning and fantastically-enthralling all-in-one.! YOU are APPRECIATED......
This is pure scientific gold! Thank you so much. I am a science dad too and I used your videos with my kids. They just love this! It makes them and me ask so many interesting questions❤. A game for VR wpuld be more than awesome! I imagine to look at labeled or highlighted levels of abstraction or focus like in your videos, all in a loop to explore all the reactions. A time zoom to watch true brownian motion would be the cherry on top.
New to your work guys and am blown away by the depth of understanding to present such sophisticated visual aids. Really happy and less despair in this information age that you guys rally the diligent and dedicated to show the evidence in terms comprehensible by many. Australians as a very good axample rather than cringeworthy underdone blowhards. You save lives, 54 years old and lost for life stoked by you guys. Not dead yet .. all eyes and ears. Cheers, Damo
Thanx. It’s been a deep dive on RUclips couple of off days. I watched the history of civilization, all the wars and destruction. Then I watched a couple of physics videos, I know if I keep at it I’ll get it! 🤣🤣🤣 And then I found you guys!
These molecular biological animations are so just blowing! Awesome work Drew and Team. Thank you!
Incredible work sir. But I am astounded. How can all this near infinite complexity work altogether at once, mind boggling so, multiple machines in perfect harmony and people still think it just happened. I don't have that kind of faith. I would have a better chance of jumping off the earth, getting to Jupiter and back, holding my breath the whole time and landing whole back at my starting point on earth than the common assumptions of materialism. To say it has the "appearance" of design is a death defying leap of presumption. It must take incredible, awesome faith that defies logic to think it's all by chance.
As AI plays a greater role in clarifying movements and interactions of these molecular processes, it becomes more important to UPDATE previous depictions so that research can be further advanced. I hope there is one website with all of these previous videos (dated) that will soon indicate AI enhancements to them.
Wonderful masterpiece!!! Thank 3.000 to Drew Berry and to all the collaborators!!!
1:55 omg, i used to play that game as a kid. I literally had to hack the game files(on PC) - copying the files from a previous level to haphazardly replace the CORRUPT final level files - to even be able to play the final level of this game (otherwise it would never complete loading!). I only learned to do that after a number of years too, some of my first experience fixing PC software problems, stay at it kids & come back to old problems! 😉
Incredibly valuable work which has greatly enriched the learning and understanding of my high school students, I look forward to seeing this in VR; and why not have a video game too!!?
Merry Christmas Drew - thanks for your fantastic work. Do you have a Patreon account?
Your animations have amazed and astounded me for many years. Thank you deeply, Drew.
Many of the inner workings of our bodies are no longer unimaginable, and in fact, are extremely beautiful.
Brilliant.
PDH complex is the most astonishing enzyme. I would suggest to design animation for hemoglobin binding and releasing molecular oxygen with the conformational changes of oxy- and deoxy- Hb. Needles to say with the role of heme prosthetic group.
Thank you.
Haemoglobin and Sickle Cell Anaemia animation, originally created 20 years ago. Not as advanced as our recent productions ruclips.net/video/-1_qkwQkB_c/видео.htmlsi=jSMaR0pxmKk-GKCi
I don't think sci-fi could come up with anything more bizarre than this.. unless given a few billion years maybe
太酷了,這樣視覺化學習很容易理解神奇複雜細胞運作?" 美極了,由衷感謝! So cool! Visualization is more easier to help us to learn the amazing complexity of cell operation. Great! Thank you all.
This video touches on so many professions, technologies & disciplines. I am an Industrial Designer; the science, information & technology shared in this video is supremely applicable to my industry. Please keep on your mission of information sharing & science education.
Remember memorizing the Krebs/ Citric Acid cycle out of photocopied pages in a binder your Professor made you buy at the college bookstore for $100? Now the kids these days have this! I'm happy for the new generation though, they have more information presented in an understandable,visual learning format!
Thanks so much for taking the time to share your CAD/animation tooling and workflows.
Thank you for your time and veracity in this journey you've taken, Berry! Great to see more recent uploads while soon to complete an AS in chemistry while transferring to university for biochem. Thanks again!! ⭐
Great work! Thank you for the insight in your workflow. The integration of game engines is a (...wait for it...) game changer ;-) and I'd love to hear more about this!
thankyou so much for your art! i love it. i also loved my amiga.
Belfast Ireland 🇮🇪
So grateful for Drews Work
Unbelievable
For all of us
Anyone know more animators/channels that make videos like this? I want more molecular biology animations that depict Brownian Motion, with molecules modeled by atoms instead of electron surface.
It's nice to see the inside of a mitochondrion; I am more interested to see the inner workings of free living or parasitic prokaryotes.
Love you and your team Mr. Barry. You guys are awesome. The videos are always mind blowing. ❤️
Understands the nature of what he depicts miraculously. He is a true Michelangelo of our time.
If I could make a wish, I would like to see a short movie of a fish being eaten, digested, build in and respirated.
You are an amazing human, thank you for simplifying such a complex biological mechanical structures and mechanism to easily understandable chunks. Thank you for your work. Love your channel and your passion.
Buddy you are so awesome , you are helping to pioneer a new way of learning.Keep up the "Excellent Work!"
Love your work... Taught me how DNA, mRNA and Epigenetics works.
Great work. Known your work for a few years, but this video allowed me to get to know you a little. Thank you. Inspirational.
Nooooo, the réal Drew Berry??? :o You're my legend... Science has always been my big passion, and because of you I'm really fascinated by animation.. But I haven't found any project yet to practice both together...
So you're animation is an accurate depiction of what it really looks like
Thank you Drew, that has answered many questions I have had over the years and we have got to know you better.
Keep up the good work.
Thank you so much
You guys have helped me excell in my knowledge of the Cells
I think Dyslexic people will get the Cells
We think in puzzles
I never thought in a million years
I would get Cellular Biology....thanks guys
Belfast Ireland 🇮🇪
Phantastic to see these moleculs in action.
You called yourself a "dinosaur" because you learned techniques in the 90's...
I attended a talk given by James Blin, a pioneer in animation who worked on the famous "Mechanical Universe" series. He wrote them in FORTRAN.
It's incredible, it's all the questions I had in high school in one animation.
Congratulations on an amazing compilation of the science and art. Keep up your good work.
David Vine , DDS, Miami Beach, .
Just amazing artistry. Bdellovibrio would be proud. Thank you!
40 minutes video just went by like 5 min. So amazing!
Kudos to you and your team for making our life look beautiful
Incredible job. Your animations are really showing how beautyful the life and science can be.
I was wondering how these incredible animations were made - thank you so much for sharing!
It would be amazing to see this running in VR. Unity has good VR support, so it would mostly depend on what kind of performance you get since VR generally requires more than 2x the compute for rendering than does a 'flat' game.
I love these animations of how these Protein Machines actually work. They are amazing.
Drew Berry, you are an inspiration to me
This is Fantastic! you may be able to get past that file saving bottleneck programmatically or via network transmission!
Yes i´ve been in architectural Compter visualisation for years... but this was realy awsome..
Amazing work … so happy that I had chance to listen to your incredible skills. Many thanks 🙏
Why DO the molecules go to where they're supposed to go? Do they move by random diffusion, or is their motion powered?
Thank you for your introduction! And keep up the nice work! 👍
28:23 look like a good map for a game.
Love this stuff! So mind blowing to get to see the process. Thank you!!!!
How can I get into this with my Quest or even just on my PC?
never has 37mins seemed so short
I agree! Wish it had Drew show us a version of the more chaotic looking realistic movements, timing, and density of the individual components. He and his team do a phenomenal job of interpreting and rendering the complexities of what makes life possible. Absolutely fascinating and wondrous! ❤
Very impressive, mate. Good work.
Very nice sir 🙏
This should be turned into a simulation game. Imagine what discoveries and strategies the public might conjure up
Those molecular dynamics simulations are very nice. However, besides the length scales shown on the simulations, it will be very nice if they could also have the time scale shown as well.
This is considered science? Yes of course.
Is this art? INDEED.
Is this architecture? Obviously.
Engineering? Certainly.
Computer science? Of course. But that's how our Lord works. These are his instruments.
How those molecules which form the ATP molecule know where to go to become ATP? It was mentioned in the animation "enzymes bring together reactants", but nothing more. How smooth is this process in reality? Like each cycle of the rotor creates exactly 3 molecules each time?
See 22:04 for a "real" animation and his explanation of artistic license.
@@JohnDlugosz I see, I made it to 20:00 minutes I thought I'd finish it today. Thanks.
This video is so cool. Do you have any other videos?
ruclips.net/p/PLD0444BD542B4D7D9&si=HQe17WvA9f1Nsx78
This is mind-blowing! Thank you for making these!
Bravo, Drew!
Stupendous.
ur the best ....belfast ireland
thank u so much
"no one can make cool stuff about biology"
drew barry:
Wow... While i still don´t understand why you call Maya a game engine, i understand that the animations skillset of maya is on blockbusterlevel..
But do you also use tools like Unreal for the "REaltime" Part?
it´s realy mesmerising.. If i was young again, this could be something for me to study too.. But now as my son studies something like this, i know how much you have to learn to get there
The real-time game engine we use for production is Unity
Great work. I loved molecular animation.
This is mind blowing! Just wow.
I am just so much in love with your work...it's amazing
Oh my god it’s Drew Berry!!
Thank you for all your hard work.
Amazing work! Thanks for sharing!
Thanks a lot for all you doing!
Absolutely amazing!
Genius, mind blowing, tausend thanks
Perfect job. Great work. Amazing videos. Like 👍🤗
Many thanks for the insightful info! Your videos keep inspiring me to try something similar and I wondered how would simulating the Brownian motion work. Never thought of using a game engine, great idea!
Great work from a famous name in graphics.
wonderful...
Im so impressed by this animation
Love your work, thanks so much.
This was excellent!! -maya animator
This is beautiful.
Amazing, amazing, amazing ...
Fascinating. Thanks
This is educational gold!
So wonderful!
Middle school?!... I think what you are doing is one of the best things humans have ever did... After discovering theme....
thx for your work .